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Photodynamic Therapy (PDT) at K2 Dermatology

Photodynamic Therapy (PDT) in Boulder

Photodynamic Therapy is a physician-directed clinical procedure that targets and treats pre-skin cancer, acne, and sun damage. This treatment combines a photosensitizing medication with a controlled light source to selectively destroy abnormal or damaged skin cells while preserving surrounding healthy tissue.

PDT has been widely studied in dermatology and is most commonly used to treat actinic keratoses and other medically significant conditions caused by cumulative ultraviolet exposure. At K2 Dermatology, PDT is performed under medical supervision to ensure precise treatment planning, appropriate light selection, and close follow-up care.

What Does PDT Treat?

There are several skin conditions that PDT can treat and, in some cases, resolve completely. PDT helps clear the skin of actinic keratoses, which are premalignant growths that develop in sun-exposed areas such as the face, scalp, chest, arms, and hands. Treating these lesions early is important, as a small percentage may progress to squamous cell carcinoma if left untreated.

Some less common conditions that PDT treats include Bowen’s disease and superficial basal cell carcinoma. PDT may also be recommended for inflammatory acne when traditional therapies have been insufficient or poorly tolerated.

Because PDT treats both visible and subclinical lesions, it can address areas of sun damage that may not yet be apparent on the skin’s surface.

What To Expect

PDT is performed at our Boulder clinic in a controlled medical setting. Your dermatologist will begin by thoroughly cleansing the treatment area. Depending on your condition, a light exfoliation, microdermabrasion, or chemical peel may be performed to enhance medication penetration.

A photosensitizing solution, aminolevulinic acid, is then applied to the skin and allowed to incubate for approximately 30 minutes to three hours, depending on the condition being treated and the type of light used. Your physician will determine the most appropriate light source for your diagnosis, which may include blue light, red light, intense pulsed light, or pulsed dye laser therapy.

During light activation, patients typically experience warmth or a burning sensation. Cooling fans or chilled air are used to improve comfort throughout the procedure.

Benefits of Photodynamic Therapy

Photodynamic therapy offers several advantages as a medical dermatologic treatment:

  • Targets abnormal and precancerous cells with high specificity
  • Treats large areas of sun damage in a single session
  • Reduces the need for multiple surgical procedures in appropriate cases
  • Preserves surrounding healthy tissue
  • Can identify and treat early lesions not yet visible to the naked eye

For patients with extensive sun damage or recurrent actinic keratoses, PDT can be an important component of long-term skin cancer prevention.

Recovery and Post-Treatment Care

After treatment, the skin will be extremely light-sensitive for approximately 48 hours while the medication is metabolized. Patients must protect the treated area during this period and should avoid outdoor exposure whenever possible. If time outdoors is unavoidable, a thick, zinc-based sunscreen with a high SPF is recommended, along with protective clothing and wide-brimmed hats.

Redness, swelling, crusting, and peeling are expected and typically last one to two weeks. These effects indicate that abnormal cells are responding to treatment. Your dermatologist will provide detailed post-care instructions and guidance on when normal activities and sun exposure may safely resume.

Complications

In most cases, there are no complications or serious side effects associated with PDT. The most common post-treatment effects are redness, peeling, and temporary discomfort. More intense reactions may occur in patients with a high number of precancerous lesions, as greater medication absorption can lead to a stronger inflammatory response.

If a reaction occurs outside of expected healing patterns, patients should contact our office promptly for evaluation and guidance.

Photodynamic Therapy in Boulder

Photodynamic Therapy is a highly effective, evidence-based treatment that K2 Dermatology is proud to offer patients throughout Boulder and the surrounding communities. If you have a history of sun damage, recurrent actinic keratoses, or early skin cancer, PDT may be an important part of your medical care plan.

Contact our clinic today to schedule a consultation and determine whether photodynamic therapy is appropriate for your condition.

Frequently Asked Questions About Photodynamic Therapy

Yes. PDT is a medically recognized dermatologic procedure used to treat precancerous lesions, certain skin cancers, and inflammatory skin conditions under physician supervision.

The number of treatments depends on the condition being treated and its severity. Some patients benefit from a single session, while others may require a series of treatments spaced several weeks apart.

YPDT reduces existing precancerous cells and may lower future skin cancer risk in treated areas, but it does not eliminate the need for regular skin exams and sun protection.

Most patients experience temporary burning or stinging during light activation. Discomfort is managed with cooling measures and typically resolves shortly after treatment ends.

Patients with actinic keratoses, extensive sun damage, or select superficial skin cancers may be candidates. A dermatologic evaluation is necessary to determine if PDT is appropriate for your specific condition.

K2 Monthly Specials 2026

APRIL:

20% Off REVISION® in-office products

MAY:

20% Off eltaMD® products & Heliocare in-office 

JUNE:

$80 Chemical Peels

JULY:

20% Off Botox (20 units min.)

AUGUST:

20% Off Botox (20 units min.)